Anti-inflammatory drugs
NSAID: non-steroidal anti-inflammatory drug
DMARD: disease-modifying anti-rheumatoid drug
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- Question
- Answer
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- Which form of COX has selective inhibitors?
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- If the initial treatment of rheumatoid arthritis with education, physiotherapy, and rest don't work, which drugs are tried next?
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- What dangerous side effect caused selective COX-2 inhibitors to be banned?
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- What is the aetiology of rheumatoid arthritis?
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- Which type of eicosanoid do NSAIDs not inhibit the production of?
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- What is the aim of treatment for rheumatoid arthritis?
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- Which 2 eicosanoid types do NSAIDs inhibit the production of?
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- What are the first steps to treating rheumatoid arthritis (4)?
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- What is the mechanism of action of NSAIDs?
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- What is a dangerous side effect of non-selective COX inhibitors?
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- What is the mechanism of action of DMARDs?
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- Are DMARDs slow- or fast-acting?
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- How can side effects of steroids be minimised?
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- In which 2 ways do corticosteroids and glucocorticoids inhibit the immune response?
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- Apart from physiotherapy, which non-systemic treatments can be used to treat rheumatoid arthritis (3)?
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- If DMARD aren't sufficient to manage rheumatoid arthritis, what drugs are tried next (3)?
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- In which 4 ways do corticosteroids and glucocorticoids have anti-inflammatory activity?
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- Do DMARDs have serious side effects?
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- Do selective COX-2 or non-selective COX inhibitors cause more fatalities due to severe side effects?
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- What are the 3 main effects of NSAIDs?
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- If NSAIDs aren't sufficient to manage rheumatoid arthritis, which drugs are tried next?
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