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Most correctly guessed answers

      • What is a salt-wasting crisis due to congenital adrenal hyperplasia?
      • Lack of aldosterone causes high Na+ loss in the urine, leading to life-threatening dehydration and shock
      • 75.0%
      • What are the 2 major causes of 1° hyperaldosteronism?
      • Aldosterone-producing adrenal adenoma (60%)
        Bilateral adrenal hyperplasia (35%)
      • 75.0%
      • What does 1° hyperaldosteronism present with classically (4)?
      • Hypertension
        Hypernatraemia
        Hypokalaemia
        Alkalosis
      • 75.0%
      • Which 3 drugs are used to treat 1° hyperaldosteronism?
      • Aldosterone receptor antagonist: Spironolactone or Eplerenone
        K+-sparing diuretic: Amiloride
      • 75.0%
      • 1° hyperaldosteronism is also called [...] syndrome.
      • Conn's
      • 75.0%
      • Which blood investigation is used to diagnose 1° hyperaldosteronism?
      • Plasma aldosterone:plasma renin activity ratio
      • 75.0%
      • A plasma aldosterone:plasma renin activity ratio of [...] is indicative of 1° hyperaldosteronism.
      • >30
      • 75.0%
      • 1° hyperaldosteronism is associated with [high/low] plasma renin.
      • low
      • 75.0%
      • 2° hyperaldosteronism is associated with [high/low] plasma renin.
      • high
      • 75.0%
      • What causes 2° hyperaldosteronism?
      • Kidney perception of low intravascular volume resulting in overactivity of renin-angiotensin system
      • 75.0%
      • Is oedema a common symptom of 1° hyperaldosteronism?
      • No
      • 50.0%
      • Are aldosterone-producing adenomas more common in men or women?
      • Women
      • 50.0%
      • Why does liver failure exarcebate ascites and oedema?
      • 2° hyperaldosteronism because aldosterone is not cleared leads to Na+ and water retention by the kidney
      • 25.0%