Results and stats for "Thyroid physiology 2"
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Most correctly guessed answers
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- Which element is taken up by the thyroid to make T3 and T4?
- Iodine
- 100.0%
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- Which amino acid is used in the thyroid in addition to iodine to make T3 and T4?
- Tyrosine
- 100.0%
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- The thyroglobulin which accumulates in thyroid epithelial cells is called [...].
- colloid
- 100.0%
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- Which element do thyroid follicular cells take up?
- Iodide
- 100.0%
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- In thyroid follicular cells, iodide is oxidized to [...].
- iodine
- 100.0%
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- In thyroid follicular cells, iodine covalently attaches to the [...] amino acids of the [...] protein.
- tyrosine, thyroglobulin
- 100.0%
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- When the thyroid is stimulated by TSH, what do follicular cells do to iodinated thyroglobulin?
- Endocytose them and break them down in lysosomes
- 100.0%
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- Where in the thyroid is iodinated thyroglobulin stored?
- Lumen of follicles
- 100.0%
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- Lysosomal degradation of iodinated thyroglobulin in thyroid follicular cells results in the release of the [...] and [...] hormones.
- T3, T4
- 100.0%
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- In thyroid follicular cells, the addition of iodine to thyroglobulin yields which 2 iodinated forms of tyrosine?
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Monoiodotyrosine
Di-iodotyrosine - 100.0%
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- Which 2 forms of iodinated tyrosine are added to form T3?
- MIT + DIT
- 100.0%
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- Once they have entered cells in the periphery, where do thyroid hormones bind?
- Nuclear receptor
- 100.0%
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- How do T3 and T4 enter the cell?
- Diffusion
- 100.0%
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- Where in the cell is the T3 and T4 receptor?
- Cytoplasm
- 100.0%
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- How are thyroid epithelial cells organized?
- Follicles
- 66.7%
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- Thyroid epithelial cells secrete [...].
- thyroglobulin
- 66.7%
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- In thyroid follicular cells, iodide is [...]ed to iodine.
- oxidiz
- 66.7%
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- C/parafollicular cells of the thyroid secrete [...].
- calcitonin
- 66.7%
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- The colloid in the thyroid represents a store of thyroid hormone which can last how long?
- Weeks
- 66.7%
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- Which enzyme oxidizes iodide into iodine in the thyroid?
- Thyroid peroxidase
- 66.7%
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- What are the 3 plasma thyroid hormone-binding proteins?
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Thyroxine binding globulin
Thyroxine binding pre-albumin
Albumin - 66.7%
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- Where does thyroid hormone-receptor complex bind on DNA?
- Thyroid hormone responsive element
- 66.7%
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- What effect do high levels of iodine have on thyroid hormone synthesis?
- Inhibition
- 66.7%
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- How do high levels of iodine inhibit thyroid hormone synthesis?
- Inhibition of the iodide pump
- 66.7%
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