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Most correctly guessed answers

      • Which element is taken up by the thyroid to make T3 and T4?
      • Iodine
      • 100.0%
      • Which amino acid is used in the thyroid in addition to iodine to make T3 and T4?
      • Tyrosine
      • 100.0%
      • The thyroglobulin which accumulates in thyroid epithelial cells is called [...].
      • colloid
      • 100.0%
      • Which element do thyroid follicular cells take up?
      • Iodide
      • 100.0%
      • In thyroid follicular cells, iodide is oxidized to [...].
      • iodine
      • 100.0%
      • In thyroid follicular cells, iodine covalently attaches to the [...] amino acids of the [...] protein.
      • tyrosine, thyroglobulin
      • 100.0%
      • When the thyroid is stimulated by TSH, what do follicular cells do to iodinated thyroglobulin?
      • Endocytose them and break them down in lysosomes
      • 100.0%
      • Where in the thyroid is iodinated thyroglobulin stored?
      • Lumen of follicles
      • 100.0%
      • Lysosomal degradation of iodinated thyroglobulin in thyroid follicular cells results in the release of the [...] and [...] hormones.
      • T3, T4
      • 100.0%
      • In thyroid follicular cells, the addition of iodine to thyroglobulin yields which 2 iodinated forms of tyrosine?
      • Monoiodotyrosine
        Di-iodotyrosine
      • 100.0%
      • Which 2 forms of iodinated tyrosine are added to form T3?
      • MIT + DIT
      • 100.0%
      • Once they have entered cells in the periphery, where do thyroid hormones bind?
      • Nuclear receptor
      • 100.0%
      • How do T3 and T4 enter the cell?
      • Diffusion
      • 100.0%
      • Where in the cell is the T3 and T4 receptor?
      • Cytoplasm
      • 100.0%
      • How are thyroid epithelial cells organized?
      • Follicles
      • 66.7%
      • Thyroid epithelial cells secrete [...].
      • thyroglobulin
      • 66.7%
      • In thyroid follicular cells, iodide is [...]ed to iodine.
      • oxidiz
      • 66.7%
      • C/parafollicular cells of the thyroid secrete [...].
      • calcitonin
      • 66.7%
      • The colloid in the thyroid represents a store of thyroid hormone which can last how long?
      • Weeks
      • 66.7%
      • Which enzyme oxidizes iodide into iodine in the thyroid?
      • Thyroid peroxidase
      • 66.7%
      • What are the 3 plasma thyroid hormone-binding proteins?
      • Thyroxine binding globulin
        Thyroxine binding pre-albumin
        Albumin
      • 66.7%
      • Where does thyroid hormone-receptor complex bind on DNA?
      • Thyroid hormone responsive element
      • 66.7%
      • What effect do high levels of iodine have on thyroid hormone synthesis?
      • Inhibition
      • 66.7%
      • How do high levels of iodine inhibit thyroid hormone synthesis?
      • Inhibition of the iodide pump
      • 66.7%