Cell cycle and cancer
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- Question
- Answer
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- What is metaplasia?
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- What is hypertrophy?
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- What is hyperplasia?
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- What are the 2 classes of proteins involved in regulation of the cell cycle?
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- Are CDK protein levels constant in the cell during the cell cycle?
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- Are cyclin protein levels constant in the cell during the cell cycle?
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- The protein family [...] regulates the activity of CDKs during the cell cycle.
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- What is neoplasia?
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- What are the 3 types of cells in terms of their ability to regenerate? Give an example of each.
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- What is dysplasia?
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- [...] is a change in cellular phenotype.
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- According to Willis, a [...] is an abnormal mass of tissue with excessive and uncoordinated growth which continues even when the stimulus is ceased.
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- What is the parenchyma of a tumour?
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- In a tumour, the clonal mutant cells are referred to as the [...] in contrast to the stroma.
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- Is the stroma of a tumour made up of clonal tumour cells?
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- The supporting connective tissue, blood vessels, and lymphatics of a tumour are called the [...].
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- A [...] is a benign tumour projecting from a mucous membrane.
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- A [...] is a benign tumour in a closed sac, with a distinct membrane and division compared to the nearby tissue.
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- A [...] is a benign epithelial tumor growing exophytically in finger-like fronds.
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- What are the 3 types of benign tumours by shape?
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- A [...] is a tumour which contains ectoderm, endoderm, and mesoderm.
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- What is the naming convention for malignant tumours of epithelial cell origin?
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- What is the naming convention for malignant tumours of mesenchymal cell origin?
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- Are carcinomas or sarcomas more common?
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- How do carcinomas first spread through the body?
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- How do sarcomas first spread through the body?
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- What is meant by “carcinoma in situ”?
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- Are benign tumours generally well-differentiated?
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- Are malignant tumours generally well-differentiated?
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- What does anaplastic mean?
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- [...] means poorly differentiated.
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- How does prognosis correlate with differentiation of tumour cells?
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- How fast do benign tumours generally grow?
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- How fast do malignant tumours generally grow?
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- How does the growth rate of a tumour correlate with the level of differentiation?
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- The [...] of a tumour is based on its degree of localization and spread.
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- The [...] of a tumour is based on its degree of cellular differentiation based on histological appearance.
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- What is desmoplasia?
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- [...] is fibrous tissue formation in response to neoplasm.
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- Is a tumour's grade or stage have the greater prognostic value?
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- Are benign tumours generally encapsulated?
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- Are malignant tumours generally encapsulated?
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- Do benign tumours metastasize?
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- Do malignant tumours metastasize?
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- Do all tumours metastasize in the same way?
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- What determines where a tumour metastasizes?
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- What is the stroma of a tumour?
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- What are the 3 reversible -plasias?
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- What are the 3 irreversible -plasias?
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- [...] is an increase in the number of cells.
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- [...] is the transformation of one differentiated cell type into another differentiated cell type.
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- [...] is a change in cellular phenotype which is commonly neoplastic.
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- What is anaplasia?
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- [...] is abnormal lack of differentiation of cells.
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- [...] is an abnormal and uncontrolled clonal proliferation of cells.
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