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NSAID: non-steroidal anti-inflammatory drug
DMARD: disease-modifying anti-rheumatoid drug

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Related quizzes

Most correctly guessed answers

      • What is the mechanism of action of NSAIDs?
      • COX inhibitor
      • 55.6%
      • Which form of COX has selective inhibitors?
      • COX-2
      • 55.6%
      • Are DMARDs slow- or fast-acting?
      • Slow-acting
      • 55.6%
      • What is the mechanism of action of DMARDs?
      • Large range
      • 55.6%
      • If NSAIDs aren't sufficient to manage rheumatoid arthritis, which drugs are tried next?
      • DMARD
      • 50.0%
      • Do DMARDs have serious side effects?
      • Yes
      • 50.0%
      • What is the aetiology of rheumatoid arthritis?
      • Unknown
      • 44.4%
      • What is the aim of treatment for rheumatoid arthritis?
      • Symptom relief, conservation of joints, and suppression of active disease
      • 44.4%
      • If the initial treatment of rheumatoid arthritis with education, physiotherapy, and rest don't work, which drugs are tried next?
      • NSAIDs
      • 44.4%
      • If DMARD aren't sufficient to manage rheumatoid arthritis, what drugs are tried next (3)?
      • Biologics, steroids, cytotoxics
      • 44.4%
      • What are the 3 main effects of NSAIDs?
      • Analgesic, anti-pyretic, anti-inflammatory
      • 44.4%
      • Which 2 eicosanoid types do NSAIDs inhibit the production of?
      • Prostaglandins and thromboxanes
      • 44.4%
      • What is a dangerous side effect of non-selective COX inhibitors?
      • Gastro-intestinal bleeding (gut and kidney)
      • 44.4%
      • What dangerous side effect caused selective COX-2 inhibitors to be banned?
      • Doubles risk of heart attack and sudden death
      • 44.4%
      • How can side effects of steroids be minimised?
      • Give locally instead of systemically
      • 44.4%
      • What are the first steps to treating rheumatoid arthritis (4)?
      • Patient education (exercise and diet for weight loss), physiotherapy, rest/exercise, OTC painkillers
      • 33.3%
      • Which type of eicosanoid do NSAIDs not inhibit the production of?
      • Leukotrienes
      • 33.3%
      • In which 2 ways do corticosteroids and glucocorticoids inhibit the immune response?
      • Inhibit T lymphocyte proliferation and induce apoptosis in immune cells
      • 33.3%
      • Apart from physiotherapy, which non-systemic treatments can be used to treat rheumatoid arthritis (3)?
      • Topical creams, intra-articular steroids, surgery
      • 27.8%
      • In which 4 ways do corticosteroids and glucocorticoids have anti-inflammatory activity?
      • Inhibit arachidonic acid release, inhibit cytokines, down-regulate adhesion molecules, inhibit COX and iNOS
      • 27.8%
      • Do selective COX-2 or non-selective COX inhibitors cause more fatalities due to severe side effects?
      • Similar numbers
      • 22.2%