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Anti-inflammatory drugs

NSAID: non-steroidal anti-inflammatory drug
DMARD: disease-modifying anti-rheumatoid drug

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      • What dangerous side effect caused selective COX-2 inhibitors to be banned?
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      • Which 2 eicosanoid types do NSAIDs inhibit the production of?
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      • Do selective COX-2 or non-selective COX inhibitors cause more fatalities due to severe side effects?
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      • In which 4 ways do corticosteroids and glucocorticoids have anti-inflammatory activity?
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      • In which 2 ways do corticosteroids and glucocorticoids inhibit the immune response?
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      • If NSAIDs aren't sufficient to manage rheumatoid arthritis, which drugs are tried next?
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      • If DMARD aren't sufficient to manage rheumatoid arthritis, what drugs are tried next (3)?
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      • What is the aetiology of rheumatoid arthritis?
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      • What is a dangerous side effect of non-selective COX inhibitors?
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      • What are the 3 main effects of NSAIDs?
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      • Which type of eicosanoid do NSAIDs not inhibit the production of?
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      • How can side effects of steroids be minimised?
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      • What is the mechanism of action of DMARDs?
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      • If the initial treatment of rheumatoid arthritis with education, physiotherapy, and rest don't work, which drugs are tried next?
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      • Are DMARDs slow- or fast-acting?
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      • What are the first steps to treating rheumatoid arthritis (4)?
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      • Apart from physiotherapy, which non-systemic treatments can be used to treat rheumatoid arthritis (3)?
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      • What is the mechanism of action of NSAIDs?
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      • Do DMARDs have serious side effects?
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      • What is the aim of treatment for rheumatoid arthritis?
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      • Which form of COX has selective inhibitors?
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Tags

Sc14, Sc14l03, Immunology, Pharmacology

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