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Results and stats for "Calcium homeostasis: disease"

Mark yourself on your knowledge of bone metabolism and related diseases.

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Most correctly guessed answers

      • What effect does ageing have on the absorption of Ca2+?
      • Lowers absorption
      • 73.0%
      • [...]calcaemia can lead to ectopic calcification.
      • Hyper
      • 73.0%
      • At which stage in life are women likely to develop osteoporosis?
      • Post-menopause
      • 73.0%
      • [...]calcaemia leads to a hypoexcitable nervous system.
      • Hyper
      • 70.3%
      • Why do children in the tropics not get rickets?
      • High exposure to sun leads to vitamin D production in skin
      • 70.3%
      • In osteoporosis, there a [...] amount of bone and a [...] mineral/matrix ratio.
      • reduced; normal
      • 70.3%
      • The following are symptoms of which disease?
        Protruding forehead, pigeon chest, kyphosis, bending of long bones, rickety rosary (costochondral swelling)
      • Rickets
      • 67.6%
      • [...]calcaemia can lead to tetany.
      • Hypo
      • 67.6%
      • Ca2+ absorption requires vitamin [...].
      • D
      • 64.9%
      • How is rickets treated (2)?
      • Increase vitamin D by eating fish oil and increasing exposure to sun
      • 64.9%
      • Why do Scandinavian children not get rickets?
      • High consumption of fish and therefore of vitamin D
      • 64.9%
      • In osteomalacia, there a [...] amount of bone and a [...] mineral/matrix ratio.
      • normal; reduced
      • 64.9%
      • Which drugs increase the risk of osteoporosis?
      • Corticosteroids
      • 64.9%
      • What is Strontium used to treat?
      • Osteoporosis
      • 64.9%
      • What is Bisphosphonate used to treat?
      • Osteoporosis
      • 64.9%
      • [...]calcaemia leads to a hyperexcitable nervous system.
      • Hypo
      • 62.2%
      • Why are post-menopausal women more at risk of osteoporosis?
      • Oestrogen deficiency
      • 62.2%
      • What effect do basic amino acids have on Ca2+ absorption?
      • Increase
      • 59.5%
      • What effect does phytic acid have on Ca2+ absorption?
      • Decrease
      • 59.5%
      • What effect does lactose have on Ca2+ absorption?
      • Increase
      • 56.8%
      • Men should eat [...] g/day of Ca2+.
      • 1
      • 54.1%
      • What is the main excretion route of Ca2+?
      • Faeces
      • 54.1%
      • [...] is the softening of bones caused by defective bone mineralization.
      • Osteomalacia
      • 54.1%
      • What are the 3 forms of Ca2+ in the plasma?
      • Free ionic (biologically active), plasma proteins, complexed (e.g. with citrate)
      • 51.4%
      • Plasma Ca2+ <[...] mM is lethal.
      • 1.5 mM
      • 51.4%
      • [...] is the reduction of bone density to 2.5 SD below the mean.
      • Osteoporosis
      • 51.4%
      • There is about [...] kg of Ca2+ in the bones in the form of hydroxyapatite.
      • 1
      • 48.6%
      • In which form is most Ca2+ found in plasma?
      • Free ionic
      • 48.6%
      • Plasma Ca2+ >[...] mM is lethal.
      • 3.75 mM
      • 45.9%
      • [...] is an element which, when given as a drug, increases bone density.
      • Strontium
      • 45.9%
      • Plasma Ca2+ is [...]-[...] mM.
      • 2.2-2.6
      • 43.2%
      • What is the mechanism of action of Strontium?
      • Increases bone growth
      • 43.2%
      • What are the 5 ways of treating osteoporosis?
      • Increase Ca2+ intake; Oestrogen replacement/receptor modulator; Strontium; Bisphosphonate; PTH
      • 43.2%
      • Why is whole bread reinforced with Ca2+?
      • Because fibre (phytic acid) lowers Ca2+ absorption
      • 40.5%
      • What is the mechanism of action of Bisphosphonate?
      • Osteoclast inhibitor
      • 37.8%
      • [...] is a chronic disorder that results in enlarged and misshapen bones due to accelerated remodelling.
      • Paget's disease
      • 35.1%